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High Quality Gssg/L-Glutathione, Oxidized CAS 27025-41-8

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High Quality Gssg/L-Glutathione, Oxidized CAS 27025-41-8

We thinks what customers think, the urgency of urgency to act during the interests of a purchaser position of theory, allowing for much better good quality, lower processing costs, prices are extra reasonable, won the new and old buyers the support and affirmation for GSH Bio Tech Pharmaceutical Raw Materials 99% High Quality Oxidized L-Glutathione. Each product goes through rigorous testing to ensure optimal performance. Friends from all over the world come to visit our factory. It is our great honor to exchange experience and achieve cooperation with them. You will be cordially welcomed! We always take innovation and integrity as our tenet, as always, provide high-quality products, perfect services, and work together to develop and create success!

what is oxidized glutathione?

Glutathione Oxidized (GSSG) powder is obtained by oxidizing the GSH rich in yesat by microbial fermentation, and then separated and purified by modern technology.Oxidized Glutathione is widely present in organisms and mainly plays a role of redox electron transfer. It can protect red blood cells from oxidative damage and keep the hemoglobin in cysteinein a reduced state.

Product Properties

CAS No.27025-41-8
FormulaC20H32N6O12S2
AppearanceWhite powder
Heavy metalsNot more than 10ppm
Purity ( HPLC )NLT 98.0%
Loss on dryingNot more than 0.5%
Model NO.GSSG
HS Code2930909099

 

L-Glutathione Oxidized Function

L-Glutathione Oxidized Function

Application of glutathione in medical field

In view of the multiple roles of glutathione in cell physiology, clinical studies to alter glutathione homeostasis have also received attention.

The list of conditions associated with impaired glutathione homeostasis continues to grow and reflects the importance and diversity of glutathione cell function.

The most well-known include neurodegenerative diseases (particularly Parkinson's and Alzheimer's diseases), lung diseases (chronic obstructive pulmonary disease, asthma and acute respiratory distress syndrome), cystic fibrosis, immune diseases (HIV, autoimmune diseases), cardiovascular diseases (hypertension, myocardial infarction, cholesterol oxidation), And age-related oxygen-related diseases (such as cataracts, macular degeneration, hearing impairment, and glaucoma), as well as the aging process itself.

Although sufficient glutathione is an important defense against many carcinogens, several cancer types have been shown to have elevated GSH levels, making them more resistant to apoptosis and chemotherapy/radiotherapy.

Although therapies that enhance glutathione synthesis, such as n-acetylcysteine, may prevent chemotherapy-related toxicity, it may also be necessary to restrict its intake during treatment of specific cancer cell lines.

In the liver, glutathione (GSH) plays a particularly important role as an antioxidant. In the treatment of viral liver disease, reduced glutathione can enhance the detoxification function of the liver through transmethylation and transpropylamino reaction, and promote bile metabolism, thereby protecting liver cells.

In the treatment of drug-induced liver disease, glutathione can effectively reduce the side effects of drugs and protect the liver.

In the treatment of alcoholic liver disease, glutathione can accelerate free radical excretion, reduce liver cell damage, restore liver detoxification function, and promote liver function recovery.

Oxidative stress is a pathophysiological marker of metabolic liver disease, and GSH is used in the treatment of NAFLD as well as other types of liver disease.

FAQ

1. Are you a manufacturer or trading company?
A: We are a manufacturer and welcome to visit our factory.

2. How to confirm the product quality before place an order?
A: We can provide you with a sample. Also, we have the inspection report issued by the authoritative third-party testing agency.

Company ProfileTEAM

glutathione factory / Glutathione Manufacturer / glutathione supplier / china glutathione manufacturers

Our Certifications

certifications

Innovation, excellent and reliability are the core values of our business. These principles today extra than ever form the basis of our success as an internationally active mid-size company for High Quality Oxidized L-Glutathione , GSSG , Oxidized Glutathione Powder , We warmly welcome all perspective inquiries from home and abroad to cooperate with us, and look forward to your correspondence.

What is L-Glutathione Oxidized used for?

L-glutathione oxidized, or simply oxidized glutathione, plays a crucial role in the body's antioxidant defense system. While the reduced form of glutathione is active and directly involved in neutralizing free radicals, the oxidized form acts as a reservoir of sorts. It can be converted back into the reduced, active state when needed, replenishing the antioxidant stores. This dynamic interplay ensures a continuous supply of active glutathione for combating oxidative stress and maintaining cellular health.

What is the difference between oxidized and reduced glutathione?

Reduced glutathione (GSH) is the active antioxidant form, while oxidized glutathione (GSSG) results from GSH neutralizing free radicals. The dynamic interplay between GSH and GSSG maintains cellular redox balance.

What is the solubility of oxidized glutathione?

The solubility of glutathione oxidized in PBS (pH 7.2) is approximately 10 mg/ml. Oxidized glutathione (GSSG) has limited solubility in water, affecting its bioavailability. GSSG tends to form insoluble aggregates, which can impact its physiological functions compared to the more soluble reduced glutathione (GSH).

What happens when glutathione is oxidized?

When glutathione is oxidized, it transforms into its oxidized form, GSSG. This change reduces its antioxidant capacity. GSSG can be recycled back to its active state through enzymatic processes, crucial for maintaining cellular health and combating oxidative stress.

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