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With the in-depth study of scientific anti-aging mechanisms, β-Nicotinamide Mononucleotide (NMN), as a form of vitamin B3, has gradually become a rising star in the cosmetics industry. The role of NMN in cosmetics is mainly based on its key role in cellular energy metabolism and antioxidant defense system.
NAD+ (nicotinamide adenine dinucleotide) is an important coenzyme in cells, which is widely involved in the energy metabolism and signal transduction process of cells. With the increase of age, the level of NAD+ in the body gradually decreases, which is closely related to the aging process. As a direct precursor of NAD+, NMN can effectively increase the level of NAD+ in cells, thus showing great potential in anti-aging.
The antioxidant properties of NMN are an important basis for its application in cosmetics. It can directly remove free radicals or enhance the antioxidant capacity of cells to help maintain skin homeostasis. This is elaborated in detail in a review article published in the journal "Antioxidants". NMN replenishes the NAD+ pool, restores the energy state of cellular mitochondria, alleviates oxidative stress and inflammatory responses, strengthens the extracellular matrix and skin barrier, and inhibits the skin pigmentation process.
The application of NMN in skin health is not limited to its antioxidant effect. It can also regulate cell aging and epidermal differentiation through multiple mechanisms. For example, NMN is able to improve the extracellular matrix in aged skin, increase the synthesis of collagen and elastin, and reduce the activity of matrix metalloproteinases, thereby counteracting the effects of natural aging and photoaging.
According to the results of clinical trials in the literature, topical application of NMN showed good tolerability on the skin, and no serious side effects were observed. This makes NMN a safe and effective cosmetic ingredient.
NMN has broad application prospects in cosmetics. It can be used alone or in combination with other active ingredients to reduce the progression of skin aging and pigmentation. In addition, the safety and effectiveness of NMN have been confirmed in multiple clinical studies, providing consumers with a new anti-aging and skin whitening option.
References: [1] Boo Y C. Mechanistic basis and clinical evidence for the applications of nicotinamide (niacinamide) to control skin aging and pigmentation[J]. Antioxidants, 2021, 10(8): 1315.
*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.
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