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Among athletes and fitness enthusiasts, the desire for superior performance and rapid recovery never ceases. In recent years, oral adenosine-5'-triphosphate (ATP) supplements have attracted widespread attention as a potential performance enhancer.
ATP, as the main energy source for body cells, not only plays a vital role within cells, but also affects muscle excitability and vasodilation through extracellular pathways.
According to research published in the Journal of the American College of Nutrition, ATP supplements can maintain muscle ATP levels after exercise and prevent their decline. In a double-blind, placebo-controlled trial of 42 healthy men, two weeks of ATP supplementation significantly increased post-exercise ATP, ADP, and AMP levels and preserved muscle excitability during repeated sprints. , thereby improving athletic performance.
In terms of cardiovascular health, ATP supplementation has shown potential to improve post-exercise hemodynamic and autonomic parameters in hypertensive women. Studies have found that ATP supplementation can promote heart rate variability recovery after exercise and reduce systolic blood pressure, which may have a positive impact on cardiovascular health in patients with hypertension.
Systematic reviews and meta-analyses further confirmed the positive effects of ATP supplementation on anaerobic performance in healthy resistance-trained individuals. Studies have found that ATP supplementation significantly increases maximal strength, although the effect on maximal repetitions or maximal anaerobic power is not significant. This suggests that ATP supplementation may be particularly beneficial in sports that require explosive power and high-intensity exercise over short periods of time.
A review article in the Journal of Functional Foods takes an in-depth look at the bioavailability of ATP supplementation and its overall benefits for health and athletic performance. Research shows that ATP supplementation not only reduces fatigue and increases strength and power, but also improves body composition, maintains muscle health, and increases recovery from stress and reduces pain.
It is believed that future research will focus on the dose-effect relationship between ATP supplementation and sports performance, as well as the synergistic effect with other nutritional supplements, to provide athletes and fitness enthusiasts with more personalized and scientific supplement strategies.
[1] González-Marenco R, Estrada-Sánchez I A, Medina-Escobedo M, et al. The Effect of Oral Adenosine Triphosphate (ATP) Supplementation on Anaerobic Exercise in Healthy Resistance-Trained Individuals: A Systematic Review and Meta-Analysis[J ]. Sports, 2024, 12(3): 82.
[2] Purpura M, Rathmacher J A, Sharp M H, et al. Oral adenosine-5′-triphosphate (atp) administration increases postexercise atp levels, muscle excitability, and athletic performance following a repeated sprint bout[J]. Journal of the American College of Nutrition, 2017, 36(3): 177-183.
[3] De Freitas M C, Ricci-Vitor A L, Freire R V, et al. Oral adenosine 5′-triphosphate supplementation improved hemodynamic and autonomic parameters after exercise in hypertensive women[J]. Journal of exercise rehabilitation, 2018, 14(4) : 671.
[4] Jäger R, Purpura M, Rathmacher J A, et al. Health and ergogenic potential of oral adenosine-5′-triphosphate (ATP) supplementation[J]. Journal of Functional Foods, 2021, 78: 104357.
*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.
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