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How to use Coenzyme Q10?

by: GSHWORLD time: 2025-03-12 classify: Product News

 

Coenzyme Q10 (CoQ10), also known as ubiquinone, is a fat-soluble, vitamin-like molecule that is widely present in human cell membranes. It plays an important role in the human body. It not only participates in cellular energy metabolism, but also has many potential benefits such as antioxidants. Its application range is wide, covering multiple fields such as adjuvant treatment of cardiovascular disease, antioxidant protection, symptom relief of specific diseases, and delaying cell aging.


1. Adjuvant treatment of cardiovascular disease


Coenzyme Q10 has potential value in the treatment of cardiovascular disease. The 2022 guidelines of the American College of Cardiology (ACC), the American Heart Association (AHA), and the Heart Failure Society (HFSA) pointed out that Coenzyme Q10 supplements can effectively reduce vascular mortality, all-cause mortality, and the number of hospitalizations in patients with heart failure, but long-term supplementation is required. In addition, a systematic review showed that supplementing patients with moderate to severe heart failure with Coenzyme Q10 on the basis of standard treatment can alleviate symptoms and reduce the incidence of major adverse cardiovascular events. Coenzyme Q10 may have a positive effect on the cardiovascular system by improving the energy metabolism of myocardial cells and reducing oxidative stress.


Coenzyme Q10 powder


2. Antioxidant protection and chronic disease prevention


Coenzyme Q10 is an effective antioxidant that can neutralize free radicals and reduce the damage to cells caused by oxidative stress. Oxidative stress plays an important role in the occurrence and development of many chronic diseases, such as diabetes, cancer, and neurodegenerative diseases. Patients with these diseases often have low levels of coenzyme Q10, and supplementing with coenzyme Q10 may help enhance the body's antioxidant capacity and delay disease progression. For example, for individuals with hypertension, coenzyme Q10 may have a certain positive effect on blood pressure control by increasing the production of important antioxidant enzymes such as superoxide dismutase and reducing vascular oxidative stress.


Antioxidant protection and chronic disease prevention


3. Relieve symptoms of specific diseases


In addition, Coenzyme Q10 has also made some research progress in relieving migraine symptoms. Some studies have shown that Coenzyme Q10 supplements can reduce the frequency, severity and duration of migraine attacks, which may be related to its improvement of mitochondrial function and reduction of oxidative stress. In terms of muscle diseases, since statins inhibit the synthesis of Coenzyme Q10, they may cause adverse reactions such as muscle pain and cramps, and supplementing Coenzyme Q10 may help relieve these symptoms.


Relieve symptoms of specific diseases


4. Delaying cell aging


Cell aging is an important part of the aging of organisms, and Coenzyme Q10 has a potential role in delaying cell aging. A study explored the in vitro antioxidant effect of Coenzyme Q10 on the metabolism of aged mesenchymal stem cells. The study found that Coenzyme Q10 can enhance mitochondrial respiratory function and improve the spare respiratory capacity of cells, especially in aged cells. It can also improve the fatty acid metabolism of cells, increase the content of saturated fatty acids, and reduce the content of monounsaturated fatty acids. In addition, CoQ10 can also affect the expression of oxidative stress-related genes and deacetylases, activate SIRT1 and SIRT3, and then increase the expression of PPARγ and CAT, thereby reducing oxidative stress and delaying the cellular aging process. These findings provide a scientific basis for the use of CoQ10 in anti-aging treatment.


Although CoQ10 has many potential benefits, there are still some things to be aware of when using it. CoQ10 supplements are generally well tolerated, but may cause some mild adverse reactions. Therefore, when using CoQ10 supplements, you should consult a doctor or pharmacist for advice, especially for people who are taking other medications or have specific diseases.


References:

[1] Sood B, Patel P, Keenaghan M. Coenzyme Q10[M]//StatPearls [Internet]. StatPearls Publishing, 2024.

[2] Ivan A, Lukinich-Gruia A T, Cristea I M, et al. In Vitro Antioxidant Effects of Coenzyme Q10 on Cellular Metabolism in Aged Mesenchymal Stem Cells[J]. Applied Sciences, 2025, 15(5): 2783.

*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.

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