How is the application of NMN in the health field?

 

With the increasing aging of the global population, the focus on healthspan has been continuously rising. Nicotinamide Mononucleotide (NMN) has garnered widespread attention for its potential role in anti-aging and metabolic health. NMN is a direct precursor of nicotinamide adenine dinucleotide (NAD⁺) and is widely involved in various physiological processes, including cellular metabolism, DNA repair, and cellular senescence.

Applications of NMN in the Health Field

The potential of NMN in anti-aging and metabolic health mainly stems from its ability to regulate NAD⁺ levels. NAD⁺ is a key coenzyme in many intracellular metabolic reactions, and its levels decline with age, leading to cellular dysfunction and the onset of age-related diseases. Studies have shown that NMN supplementation can effectively increase NAD⁺ levels in blood and tissues, thereby improving various physiological functions.

In terms of metabolic health, NMN has been proven to improve obesity and metabolic disorders. For example, in a mouse model of obesity induced by a high-fat diet, NMN supplementation significantly enhanced insulin sensitivity, increased mitochondrial numbers, and improved energy metabolism. Additionally, NMN can also improve metabolic health by modulating the function of immune cells and reducing chronic inflammation.

In the field of anti-aging, the effects of NMN are particularly remarkable. Multiple animal experiments have shown that NMN supplementation can extend healthspan, improve vascular elasticity, enhance muscle strength, and reduce cellular senescence. Moreover, NMN can protect cells from DNA damage by activating DNA repair proteins (such as PARP1), thereby delaying the aging process.

Although the potential of NMN in anti-aging and metabolic health has been widely recognized, its long-term safety and optimal dosage still require further research. In summary, as an emerging anti-aging molecule, NMN offers new hope for the health field with its potential to improve metabolic health and delay aging. With the deepening of research and the advancement of technology, NMN is expected to become a widely used health supplement in the future, helping people achieve a healthier and longer life.

References:

[1] Song, Q., Zhou, X., Xu, K., Liu, S., Zhu, X., & Yang, J. (2023). The Safety and Antiaging Effects of Nicotinamide Mononucleotide in Human Clinical Trials: an Update. Advances in Nutrition, 14(10), 1416–1435. 

[2] Zheng, C., Li, Y., Wu, X., Gao, L., & Chen, X. (2024). Advances in the Synthesis and Physiological Metabolic Regulation of Nicotinamide Mononucleotide. Nutrients, 16(14), 2354. 

*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.

by GSHWORLD

GSHWORLD is China Biological API Manufacturer. China NMN Supplements powder suppliers & best NMN benefits raw material Factory.