How does citicoline affect cognitive and memory abilities?

 

With the advancement of science, we have gained a deeper understanding of how to maintain brain health. Citicoline, a compound that plays a role in the construction of cell membranes and the synthesis of neurotransmitters, has shown potential benefits for cognitive function in some studies.

Citicoline: A Supporter of Cognitive Function

As an important component of cell membranes and a precursor of acetylcholine, citicoline may contribute to the maintenance of cognitive functions. Research indicates that it may have a positive impact on memory and cognitive abilities, especially in the elderly population.

Improving Memory: According to multiple studies, citicoline has a positive effect on improving the memory of older adults. It can increase the level of acetylcholine in the brain, a neurotransmitter closely related to memory and cognitive functions.

Results of Clinical Trials: In some randomized controlled trials, healthy older adults showed significant improvements in memory tests after taking citicoline, particularly in episodic memory.

Comprehensive Memory Performance: The supplementation of citicoline not only improves specific types of memory but also enhances overall memory performance. Some studies have shown that older adults who took citicoline scored higher in various memory tests compared to the placebo group.

Scientific Research: Cautious Optimism

Numerous scientific studies point out that citicoline may help improve or maintain cognitive functions. However, these research results need to be verified in studies with larger samples and longer durations. Currently, scientists maintain a cautiously optimistic attitude towards the effects of citicoline.

Research on citicoline provides us with the possibility of exploring new avenues for cognitive health. However, it is important to remember that everyone's health condition is unique; therefore, seeking professional medical advice before taking any new health measures is crucial.

References：

[1]  Gareri, P., Cotroneo, A. M., Montella, R., Gaglianone, M., & Putignano, S. (2024). Citicoline: A Cholinergic Precursor with a Pivotal Role in Dementia and Alzheimer’s Disease. Journal of Alzheimer’s Disease, 100(725-733). DOI: 10.3233/JAD-240497

[2] Bonvicini, M., Travaglini, S., Lelli, D., Antonelli Incalzi, R., & Pedone, C. (2023). Is Citicoline Effective in Preventing and Slowing Down Dementia?—A Systematic Review and a Meta-Analysis. Nutrients, 15(386). DOI: 10.3390/nu15020386

[3] Nakazaki, E., Mah, E., Sanoshy, K., Citrolo, D., & Watanabe, F. (2021). Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. The Journal of Nutrition, 151(2153-2160). DOI: 10.1093/jn/nxab119

[4] Kansakar, U., Trimarco, V., Mone, P., Varzideh, F., Lombardi, A., & Santulli, G. (2023). Choline supplements: An update. Frontiers in Endocrinology, 14(1148166). DOI: 10.3389/fendo.2023.1148166

[5]Synoradzki, K., & Grieb, P. (2019). Citicoline: A Superior Form of Choline? Nutrients, 11(1569). DOI: 10.3390/nu11071569

*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.

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