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As we age, the skin gradually loses its elasticity and luster, and wrinkles and sagging follow. Anti-aging skin care has become a hot topic in the field of modern skin care. In recent years, adenosine, as an anti-aging ingredient, has received widespread attention and research.
Adenosine is an endogenous nucleoside widely present in the human body, composed of adenine and ribose. It not only participates in the physiological activities of cells, but also acts through specific adenosine receptors. Adenosine receptors belong to the G protein-coupled receptor family and are mainly divided into four subtypes: A1, A2A, A2B and A3. In the skin, A1 and A2A receptors are mainly expressed.
1. Promote collagen production: In the dermis, adenosine stimulates the production of collagen through A2A receptors. Collagen is a key protein that maintains skin elasticity and structure. With age, its synthesis decreases, resulting in wrinkles and sagging of the skin. Adenosine can stimulate new collagen synthesis, thereby improving skin elasticity and moisture and reducing wrinkles.
2. Stimulate fat production: In subcutaneous tissue, adenosine promotes fat production and fat cell production through A1 receptors. As we age, facial subcutaneous fat tissue decreases, causing the skin to lose support, sag and wrinkle. Adenosine can promote the growth of fat cells and improve skin firmness.
3. Increase DNA synthesis and protein synthesis: Adenosine can increase new DNA synthesis and protein synthesis, which is essential for the renewal and repair of skin cells.
4. Anti-inflammatory effect: Adenosine helps repair and protect the skin by inhibiting the activity of inflammatory cells and reducing the inflammatory response of the skin.
Adenosine, as a safe and effective anti-aging ingredient, has been widely used in various skin care products. For example, products such as creams, essences and masks containing adenosine can be applied directly to the skin through external use to help reduce wrinkles and improve skin firmness and elasticity.
As an anti-aging ingredient, adenosine has shown great potential in anti-aging skin. Adenosine helps improve skin quality and reduce signs of aging by promoting collagen production, stimulating fat cell growth, increasing DNA and protein synthesis, and anti-inflammatory effects. However, everyone's skin conditions and needs are different. Only by choosing skin care products that suit you and using them consistently can you achieve the best anti-aging results.
[1] Marucci G, Buccioni M, Varlaro V, Volpini R, Amenta F. The possible role of the nucleoside adenosine in countering skin aging: A review. Biofactors. 2022 Sep;48(5):1027-1035. doi: 10.1002/biof.1881. Epub 2022 Aug 18. PMID: 35979986; PMCID: PMC9804842.
*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.
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