How does NMN improve intestinal health

 

With the global focus on combating aging and enhancing healthy lifespan, Nicotinamide Mononucleotide (NMN), as a key precursor of NAD+, is increasingly prominent in the field of biomedicine. NMN not only shows great potential in the field of anti-aging but also demonstrates unique advantages in the treatment of digestive system diseases.

1. NMN and Digestive System Health

NMN, a compound naturally present in food, rapidly converts into NAD+ within the human body and is crucial for maintaining cellular function and redox balance. The decline of NAD+ levels is closely related to the occurrence and development of various digestive system diseases, including liver diseases and intestinal dysfunction. Therefore, supplementing with NMN to increase NAD+ levels may be of significant importance for the prevention and treatment of these diseases.

2. The Role of NMN in Intestinal Health

Intestinal health is essential for overall health. NMN has a positive impact on maintaining the integrity of the intestinal barrier and reducing inflammation by enhancing mitochondrial function and increasing NAD+ levels. In models of inflammatory bowel disease (IBD), NMN treatment has improved intestinal morphology, restored the function of the intestinal mucosal barrier, and reduced the expression of pro-inflammatory factors in serum. Additionally, NMN can improve intestinal health by regulating the gut microbiota, increasing the abundance of probiotics, and reducing the number of harmful bacteria.

3. Progress in Clinical Research on NMN

Although the results of NMN in animal models are encouraging, its effectiveness and safety in humans are still being explored. Preliminary clinical trials have shown that a single oral dose of NMN is safe in healthy adults and can be effectively metabolized. These studies provide preliminary human data support for the application of NMN in the treatment of digestive system diseases.

NMN, as an emerging ingredient, shows great potential in improving digestive system health. Its mechanism of action in intestinal health provides new strategies for the treatment of related diseases. With in-depth research, NMN is expected to become an important means of improving digestive system health and treating related diseases, bringing more hope for human health.

References:

[1] Wen J, Syed B, Kim S, et al. Improved Physical Performance Parameters in Patients Taking Nicotinamide Mononucleotide (NMN): A Systematic Review of Randomized Control Trials[J]. Cureus, 2024, 16(8): e65961.

[2] Liao G, Xie Y, Peng H, et al. Advancements in NMN biotherapy and research updates in the field of digestive system diseases[J]. Journal of Translational Medicine, 2024, 22(1): 805.

*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.

by GSHWORLD

GSHWORLD is China Biological API Manufacturer. China NMN Supplements powder suppliers & best NMN benefits raw material Factory.