Can supplementing with Citicoline Sodium affect memory?

 

Memory is an important component of brain function, allowing us to store and recall information. Memory abilities tend to decline as we age, which is largely considered part of the natural aging process. However, for middle-aged and older adults who wish to improve or at least maintain their memory, Citicoline, a metabolite naturally present in all living cells, may offer a ray of hope.

Citicoline Sodium and Memory

Choline Deficiency and Age-Related Memory Decline: Although the body can synthesize choline, it does not synthesize enough to meet demand, so it must be obtained through the diet. Choline deficiency has been associated with memory decline in the elderly. Studies have shown that increasing choline intake can improve choline uptake by the brain, which may help reverse age-related cognitive changes.

Uridine as a precursor of nerve cell membrane phospholipids: Uridine produced by the breakdown of citicoline in the body has a positive effect on synaptic function, supporting the formation of synaptic membranes and potentially alleviating synaptic dysfunction.

Human uptake of choline and its metabolism: Magnetic resonance spectroscopy (MRS) studies have shown that citicoline intake can improve choline uptake in the brain of older adults, which is particularly important for memory function.

Intervention trials: Citicoline has been found to have a positive effect on memory efficiency in randomized, placebo-controlled trials of cognitively normal middle-aged and older adults. These studies typically use standardized tests of memory function, such as the Wechsler Memory Scale.

Although scientific research on citicoline for memory is still ongoing, existing evidence suggests that citicoline supplementation may have a positive effect on memory function in middle-aged and older adults. This finding is particularly important for older adults who are at risk for age-related memory decline. However, more research is needed to determine the long-term effects of citicoline on memory and to identify its mechanisms of action. In addition, future studies should consider individual differences, such as gender, genetic background, and lifestyle factors, which may affect the potential benefits of citicoline on memory.

References:

[1] Hersant H, He S, Maliha P, Grossberg G. Over the Counter Supplements for Memory: A Review of Available Evidence. CNS Drugs. 2023 Sep;37(9):797-817. doi: 10.1007/s40263-023-01031-6. Epub 2023 Aug 21. PMID: 37603263 .

[2] Świątkiewicz M, Grieb P. Citicoline for Supporting Memory in Aging Humans. Aging Dis. 2023 Aug 1;14(4):1184-1195. doi: 10.14336/AD.2022.0913. PMID: 37196134; PMCID: PMC10389840.

*Special note - This article is for informational purposes only and cannot replace a doctor's treatment diagnosis and advice. It should not be regarded as a recommendation or proof of efficacy of the medical products involved. If it involves disease diagnosis, treatment, and rehabilitation, please be sure to go to a professional medical institution to seek professional advice.

by GSHWORLD

GSHWORLD is China Biological API Manufacturer. China Glutathione Supplements powder suppliers & best Glutathione benefits raw material Factory.