Health experts have found two good things in the health care sector – coenzyme Q10 and PQQ, and both inside and outside may become a new anti-aging way.
When it comes to skin health, anti-aging is a top concern for the vast majority of people.
The skin care industry has launched a large number of creams, serums, masks and other products to meet people’s needs for youthful skin.
Action mechanism
PQQ
PQQ is short for pyrroloquinoline quinone, which is an essential nutrient for the human body and is called the 14th vitamin by the world medical community.
It plays a REDOX role in living systems and has the name of “King of antioxidant”, also known as “king of cell metabolism”.
It is also very rare, found only in some microbial, plant and animal tissues, and is very expensive, arguably the most expensive antioxidant in the world.
It can identify the damaged fine cells in our body, directly to the mitochondria, bottom repair, ingesting a little trace of PQQ can improve the human body’s metabolism and growth ability, so it is extremely precious.
Coenzyme Q10
Coq10 is a fat-soluble vitamin found mainly in mitochondria and cytoplasm.
It participates in important physiological processes such as energy metabolism and cell respiration in human body, and is an important electron transporter in cells.
Studies have shown that coenzyme Q10 can improve the level of intracellular energy metabolism, enhance the antioxidant capacity of cells, and reduce oxidative stress damage by regulating mitochondrial membrane potential and promoting mitochondrial respiratory chain enzyme activity.
Coq10 is important for protecting heart and blood vessel health and can reduce the risk of cardiovascular disease.
It also boosts the function of the immune system, helps to moisturize the skin and maintain a healthy state of the body.
Why is it so popular?
In human life, aging seems to involve more resignation than any other experience:
Hair turns white, wrinkles appear, teeth loosen and fall out… Along with this change, there is also a decline in physiological functions and major sensory functions, and an increase in susceptibility to a variety of health problems.
Aging is inevitable, but it is a process that can be delayed.
Therefore, since ancient times, people have always been looking for “the secret of eternal youth.”
Did you know that we go through cliffside aging several times in our lives?
The correct answer: three times
- First time I was 35
- The second time was at age 60
- The third time was at the age of 80
Mitochondria: Energy factories inside cells
In every cell, mitochondria play a vital role.
They are energy factories inside cells that produce ATP, the energy needed to sustain life.
It is estimated that up to 95% of the energy needed by a cell comes from mitochondria.
If the mitochondria stop working, the cell will not survive.
In each human cell, there are about 1,000-2,500 mitochondria.
This backup mechanism ensures that even if some of the mitochondria fail, the cell can maintain its normal energy supply.
ATP consumption and human activities
The main task of mitochondria is to help cells produce ATP, a molecule known as energy currency.
Each cell consumes about 10 billion ATP per day, and when you zoom into the perspective of the whole person, this number becomes unimaginable.
A 70 kg adult, at rest, consumes ATP equivalent to his body weight in one day, that is, 70 kg ATP.
During strenuous exercise, this figure can soar to 0.5-1 kilograms per minute.
One inconvenient fact reveals the cruel truth of life:
Humans cannot store ATP, and this vital molecule can only be used in real time as it is produced.
For example, some acute poisons, such as cyanide, can rapidly disable mitochondria, resulting in the loss of human life in a very short time.
In just seven seconds, to be precise, once the mitochondria stop working and no longer produce ATP, human life will end.
Aging, on the other hand, is a chronic process that causes mitochondrial damage and loss of function.
In other words, one of the causes of aging in the body cannot be separated from changes at the cellular level.
It is no accident, then, why PQQ and coQ10 have become hot topics in the health field.
No wonder gold is so popular
In human life, the role of PQQ is mainly reflected in anti-aging, promoting growth and development, improving cognition, improving heart function and so on, which greatly improves the quality of human life.
Coenzyme Q10 can act on the epidermis and dermis of the skin, and has the effect of promoting skin metabolism and anti-oxidation.
It is particularly important to select a suitable carrier for transporting coenzyme Q10 when it is used in anti-aging cosmetics.
The study confirmed that PQQ can improve mitochondrial function
The researchers divided the mice into a PQQ deficiency group and a PQQ supplement group, and measured the number and function of mitochondria after a PQQ diet continued for one month.
A diet supplemented with PQQ was found to stimulate the activity of the mitochondrial complex in mice.
Compared with mice supplemented with PQQ, the area occupied by mitochondria in the liver cells of PQQ deficient mice was reduced (the small dimming area corresponds to the mitochondrial cross-sectional area), and the relative number of mitochondria was reduced by 20-30%, as shown below (Figure 1, Table 2).
Respiratory quotient (RQ) is an index of mitochondrial activity.
Pq-deficient mice had lower RQ values, which was also seen as a sign of impaired mitochondrial function and inefficient use of carbohydrates.
The study found that PQQ deficient mice had reduced respiratory quotient compared with PQQ supplemented mice, suggesting that PQQ supplementation enhanced mitochondrial activity.
The study confirmed that each observation provided evidence or partial validation of the importance of PQQ for mitochondrial function.
It is the lack of PQQ that leads to a marked decline in mitochondrial content or dysfunction.
PQQ is known as a “mitochondrial optimizer” and “the energy factory of cells”, which has an antioxidant effect and can effectively remove free radicals and reduce cell damage.
Studies have found that dietary supplement PQQ can improve mitochondrial function, reduce oxidative stress and inflammatory response to play an anti-aging role.
In mitochondria, coenzyme Q10 plays a key role as an electron carrier in the process of oxidative phosphorylation and participates in the formation of mitochondrial ATP.
reference
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