By regulating the GAL promoter, cell growth was promoted at 30℃ and gene transcription was activated at 26℃

Efficient synthesis of red myrrh from Saccharomyces cerevisiae

The metabolic engineering of North Chemical Engineering team reformed Saccharomyces cerevisiae to synthesize red myrrh efficiently As a natural sesquiterpenoid compound, alpha-red myrrh has broad application prospects in medicine and cosmetics because of its unique aroma and remarkable antioxidant properties. However, in the production process of α-red myrrh, the traditional plant extraction method has limited…

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One-carbon fixation via the synthetic reductive glycine pathway exceeds yield of the Calvin cycle

Mapp uses a reductive glycine anabolic pathway to achieve carbon fixation

Energy efficient, MAPu uses a reductive glycine anabolic pathway to achieve carbon fixation and increase biomass production by 17% “If the planet were a business, carbon dioxide would be its expense and carbon sequestration its income.” At present, this “carbon account” is seriously empty. Every year, human emissions of carbon dioxide far exceed the fixed…

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Tandem GGDEF-EAL Domain Proteins Pleiotropically Modulatec-di-GMP Metabolism Enrolled in Bacterial Cellulose Biosynthesis

Tandem GGDEF-EAL domain proteins promote bacterial cellulose synthesis

Abstract Recently, Zhong Cheng/Xin Bo team of Tianjin University of Science and Technology College of Bioengineering published an article in the Journal of Agricultural and Food Chemistry: Tandem GGDEF-EAL domain proteins pleiotropically modulates c-di-GMP metabolism enrolled in bacterial cellulose Biosynthesis (https://doi.org/10.1021/acs.jafc.4c07301), which reported GGDEF – EAL tandem structure domain protein c – di – GMP…

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Combinatorial metabolic engineering of Escherichia coli to efficiently produce L-threonine from untreated cane molasses

substrate cost of L-threonine production is reduced by 48%

01 Abstract Following the work on constructing the highest L-threonine yield from polyploid Escherichia coli [LiangQuanfeng Shanshan/Qi Qingsheng group Adv Sci | Created artificial polyploid Escherichia coli and applied to threonine synthesis] published in the leading journal Advanced Science, Liang Quanfeng/Qi Qingsheng team of the State Key Laboratory of Microbial Technology of Shandong University published…

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Gut microbial-derived phenylacetylglutamine accelerates host cellular senescence

Fudan University found that this metabolite of gut flora can accelerate aging

Gut microbiota plays a crucial role in host health during aging. How the gut microbiota accelerates cellular aging and the mechanisms of its effects on human aging are still unclear. On January 10th, 2025, Chao Zhao’s team from Fudan University published an article entitled “Gut microbial-derived phenylacetylglutamine accelerates host cellular senescence” in the journal Nature…

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Systematic engineering of Escherichia coli forefficient production of nicotinamide riboside fromnicotinamide and 3-cyanopyridine

Efficient synthesis of nicotinamide riboside using Escherichia coli

In this issue, Bioresource Technology published online the research results of “Systematic engineering of Escherichia coli for efficient production of nicotinamide riboside from nicotinamide and 3-cyanopyridine” by the research group of Professor Zhou Jingwen and the team of Academician Chen Jian of Jiangnan University Future Food Science Center. Huang Zhongshi, a 2020 PhD student, is…

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