Extracellular vesicle-mediated VEGF-A mRNA delivery rescues ischaemic injury with low immunogenicity

A novel gene therapy for ischemic heart disease based on engineered external vesicles with high efficiency and low immunogenicity

Ischemic injury is the number one cause of death and disease in the world, including the United States and China, and vascular endothelial growth factor (VEGF) gene therapy holds promise for patients with ischemic injury. However, the high immunogenicity of traditional viral vectors (such as adeno-associated virus AAV) and the low expression efficiency of lipid…

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liver

Effective liver protection drugs you need to know

[Must see] Efficient liver protection, these drugs you must know! Complete analysis of pharmaceutical care Clinically, drugs that improve liver function, promote liver cell regeneration and enhance liver detoxification function are classified as hepatoprotective drugs. There are many reasons for liver cell damage, therefore, in the liver protection treatment, the cause should be removed first,…

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Adenosine

Adenosine and adenosine triphosphate (ATP)

Cardiovascular emergencies have the characteristics of acute onset, complex condition and critical condition. In clinical practice, the application of drugs for the treatment of cardiovascular emergencies plays a key role. How to realize the standardized use of emergency medicine is particularly critical. How can rescue drugs be used safely and effectively? adenosine Adenosine is a…

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