Glutathione

Clinical application of glutathione in treatment of melasma

With the in-depth study of pigmented skin diseases, the treatment methods are constantly enriched. Melasma (also known as liver spot), as a common pigmented skin disease, has a high incidence, especially in middle-aged women, causing significant distress to the appearance of patients, and adversely affecting the emotional state and mental health of patients. Glutathione (GSH),…

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glutathione

binding mechanism of glutathione and GST label protein

[Daily question] A detailed explanation of the binding mechanism of glutathione (GSH) and GST label protein The specific binding mechanism of glutathione (GSH) to glutathione S-transferase (GST) tag protein involves multiple levels of molecular interactions, and the detailed mechanism is as follows: Structural and functional background Glutathione (GSH) A tripeptide consisting of glutamic acid, cysteine,…

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Innovative mechanism of synergistic activation of glutathione and tyrosinase in melanoma diagnosis

Synergistic activation of glutathione and tyrosinase in melanoma diagnosis

Exploring Cy-Dual probes: An innovative mechanism of glutathione and tyrosinase co-activation in melanoma diagnosis Source journal impact factor and author’s academic background Research background Melanoma is a highly aggressive malignancy with a survival rate of less than 10% in advanced patients, while early diagnosis can significantly improve prognosis through surgery (80% of patients are recurrence-free…

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Glutathione

Glutathione is a natural antioxidant

Glutathione (GSH) is a naturally occurring antioxidant produced by the liver and central nervous system that is said to help metabolize toxins, break down free radicals, support immune function, and more. Researchers have explored its potential use for diseases such as cystic fibrosis, chemotherapy-related toxicity, and Parkinson’s disease. There is currently insufficient scientific evidence to…

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Maintaining redox homeostasis to regulate efficient glutathione metabolism in Corynebacterium glutamicum

Maintaining redox homeostasis to regulate efficient glutathione metabolism in Corynebacterium glutamicum

Research points This article investigates the metabolic mechanism of glutathione (GSH) as an antioxidant in Corynebacterium glutamicum, and constructs an efficient glutathione producing strain through metabolic engineering and fermentation optimization strategies. Research has found that by modifying glutathione synthase (GshF), knocking out genes related to hydrogen sulfide production and glutathione degradation, and combining with overexpression…

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liposome glutathione

Safety and detoxification effects of oral liposome glutathione

Oral liposome glutathione: An exploration of absorptive safety and detoxification effect introduction In the field of nutritional supplements, the absorption of vitamins and dietary supplements has always been a hot topic. Vitamin C, for example, although it plays an important role in maintaining human health, its bioavailability gradually decreases as the dose is consumed, especially…

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