Ischemic injury is the number one cause of death and disease in the world, including the United States and China, and vascular endothelial growth factor (VEGF) gene therapy holds promise for patients with ischemic injury. However, the high immunogenicity of traditional viral vectors (such as adeno-associated virus AAV) and the low expression efficiency of lipid…
Abstract Recently, Zhong Cheng/Xin Bo team of Tianjin University of Science and Technology College of Bioengineering published an article in the Journal of Agricultural and Food Chemistry: Tandem GGDEF-EAL domain proteins pleiotropically modulates c-di-GMP metabolism enrolled in bacterial cellulose Biosynthesis (https://doi.org/10.1021/acs.jafc.4c07301), which reported GGDEF – EAL tandem structure domain protein c – di – GMP…
When a metabolic function is “leaky” to the community (i.e., partially available to other species), microbes can save energy by stopping production of that function and relying on other species to perform it. Metabolic dependence in organisms can be formed by the loss of certain easily replaceable functions, such as the active deletion of certain…
01 Abstract Following the work on constructing the highest L-threonine yield from polyploid Escherichia coli [LiangQuanfeng Shanshan/Qi Qingsheng group Adv Sci | Created artificial polyploid Escherichia coli and applied to threonine synthesis] published in the leading journal Advanced Science, Liang Quanfeng/Qi Qingsheng team of the State Key Laboratory of Microbial Technology of Shandong University published…
Japanese scientists have found that NMN supplementation can prevent age-related hearing loss in mice. NMN inhibits age-related hearing loss Mice naturally lose their hearing as they age, just like humans do. To confirm this, we compared the hearing of 25-week-old mice (about 30 human years) with that of 12-week-old mice (about 21 human years). The…
Oral liposome glutathione: An exploration of absorptive safety and detoxification effect introduction In the field of nutritional supplements, the absorption of vitamins and dietary supplements has always been a hot topic. Vitamin C, for example, although it plays an important role in maintaining human health, its bioavailability gradually decreases as the dose is consumed, especially…
New research shows that amino acids are the main carbon source of liver fat, and long-term excessive intake may increase the burden on the liver. Carbohydrates have historically been considered the main driver of new fat in the liver, but the conversion of glucose or fructose to fatty acids in the liver is inexplicably low….
Gut microbiota plays a crucial role in host health during aging. How the gut microbiota accelerates cellular aging and the mechanisms of its effects on human aging are still unclear. On January 10th, 2025, Chao Zhao’s team from Fudan University published an article entitled “Gut microbial-derived phenylacetylglutamine accelerates host cellular senescence” in the journal Nature…
Is it curious that the “mysterious force” of this small anti-aging circle in the body – NAD+, how is it hooked with anti-aging and health? NAD+ : The “Energy Engine” in cells NAD+, the name is called nicotinamide adenine dinucleotide, although the name is difficult to pronounce, it is a super “busy person” in our…
When it comes to antioxidants, one must mention is glutathione. There is a topic “the original aging is not uniform” on the hot search news! Many netizens have found that feeling that they are suddenly getting old is probably not an illusion, but “cliff aging” really happened. In fact, on the topic of “cliff aging”,…