Glutathione is a powerful antioxidant widely used in water and light therapy, mainly for whitening, brightening skin, antioxidant and skin barrier repair.

The following is its collocation scheme, dosage and usage in the water needle and precautions:

Glutathione Common ingredients

Glutathione is often used in conjunction with other ingredients in water optics to enhance the effect:

(1). Vitamin C (L-C)

Action: synergistic antioxidant, inhibition of melanin production, brightening skin.
Combination ratio: Glutathione (200-400mg) + Vitamin C (2-5ml).

(2). Hyaluronic acid (HA)

Function: hydrating and moisturizing, promoting skin repair and relieving dryness after injection.
Combination ratio: glutathione (200mg) + hyaluronic acid (1-2ml).

(3) Tranexamic acid (Tranexamic acid)

Action: Inhibit melanin activity, improve melasma, precipitation.
Combination ratio: glutathione (200-400mg) + tranexamic acid (1-2ml).

(4). Collagen/peptides

Function: promote skin elasticity, anti-aging.

(5). Other antioxidants (such as lipoic acid, Coenzyme Q10)

Action: enhance antioxidant effect, delay photoaging.

Dosage and usage

(1). Single dosage

Glutathione: 200-400mg per treatment is recommended, adjusted according to skin condition.
Light weight: 200-300mg
Heavy color sink or anti-aging requirement: 300-400mg
Total volume: The total amount of liquid in a single water needle is usually 3-5ml (including other ingredients).

(2) Injection depth

Superficial dermis: 1.0-1.5mm (whitening, antioxidant).
Mesoderm: 1.5-2.5mm (when combined with repair components).

(3) Frequency of treatment

Initial treatment: interval 2-4 weeks, 3 consecutive times for 1 course.
Maintenance: once every 2-3 months.

Matters needing attention

(1) Contraindications

People allergic to glutathione, pregnant women, breastfeeding women, and patients with severe liver and kidney diseases are prohibited.
Avoid combined use with sulfonamides and penicillin.

(2) Side effects

Slight redness and ecchymosis (subsiding in 1-3 days).
Rare allergic reactions (skin test required).

(3) Postoperative care

Avoid water within 24 hours and use a medical repair mask within 3 days.
Strict sun protection (SPF50+, physical cover).

(4). Personalized adjustment

Adjust the concentration according to the skin sensitivity, the degree of pigmentation, the first recommended starting from the low dose (200mg).

Clinical case reference

Whitening plan: glutathione 300mg + tranexamic acid 2ml + hyaluronic acid 2ml, once a month, after 3 times to reduce the color spots by 40-60%.
Anti-aging repair solution: Glutathione 200mg + collagen 1ml + polypeptide 1ml, once every 2 months, to improve skin gloss.